E cigarettes potentially as harmful as tobacco cigarettes, study shows E cigarettes offer potentially cheaper and healthier alternative for smokers The Collegiate Live E cigarettes nearly twice as effective as other nicotine replacement therapies at helping smokers quit The nicotine in 1 vape can equal 50 cigarettes. Depending on the size of the vape and nicotine strength, it can be much higher. Nicotine can harm the developing brain, affecting Vaping vs. smoking: Long term effects, benefits, and risks